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Dr. McCarty's research is focused on understanding the interplay between cell biology and fluid mechanics in the cardiovascular system. In particular, his research into the balance between hydrodynamic shear forces and chemical adhesive interactions has great relevance to the processes underlying cardiovascular disease, inflammation, and cancer. The focus of his talk will be to highlight some of his group’s recent efforts to characterize the role that shear flow plays in regulating thrombus formation and cancer metastasis. He will also present work on emerging technologies for the detection of circulating tumor cells form peripheral blood samples.
About Dr. McCarty:
Dr. McCarty received his Ph.D. degree in chemical engineering from Johns Hopkins University, where his research focused on the identification and characterization of novel tumor cell receptors for blood platelets and leukocytes. He performed his postdoctoral research on platelet cell biology in the Pharmacology Department at the University of Oxford. Dr. McCarty joined Oregon Health & Science University, where he serves as the Vice-Chair and Director of Graduate Education for the Biomedical Engineering Department. Dr. McCarty holds an appointment as an Associate Professor of Biomedical Engineering, with joint appoints in Cell & Developmental Biology, and Hematology & Medical Oncology.