Monday, November 8, 2021 - 16:00 to 17:00
Event Speaker: 
Mingming Wu, Cornell University
Local Contact: 
Bo Sun

It is now indisputable that the biophysical and biochemical environment surrounding a tumor plays an equally important role in tumor invasion as the genetic makeup of the tumor. In this seminar, I will discuss about our efforts in understanding how single tumor cells use biochemical and biomechanical cues to ‘talk’ to their microenvironment, and how this communication dictates tumor cells’ decision to invade within a tissue like and three dimensional  biopolymer network. Breast tumor cells and spheroids are used as model systems for these studies, microfluidic platforms are developed for re-creating physiologically realistic tumor microenvironment and advanced optical imaging for  following molecular/cell  dynamics of single tumor cells.

Refreshments will be offered half an hour before the colloquium in Weniger 379